Genesis® 200


Genesis® 200 is the world’s first quantitative, fully-automated, stain-free, multi-organ, 2D & 3D multiphoton imaging system for tissue diagnostic. The now commercially available Genesis® 200 is designed to assist in both preclinical and clinical research. In the area of clinical studies, it provides pharmaceutical companies with specific morphological and extracellular matrix analysis as well as quantification for the accurate study of the progression of the disease. Genesis® 200 is able to detect any marginal improvement in treatment efficacy which is currently not available to pathologists with existing stain-based imaging techniques.

This state-of-the-art technology enhances current liver fibrosis staging with ultra-high resolution imaging and is capable of detecting fine collagen dynamics that are otherwise unobserved with conventional staining techniques. This unique advantage, combined with software algorithms that isolate and quantify morphometric features (examples include collagen string, collagen intersection and region-based collagen segmentation) enables the objective and accurate staging of liver fibrosis.


Features & Benefits

Synopsis of the different features:


Eliminate staining artifacts while shortening sample preparation time

High Resolution

Detect fine collagen fibers, up to 0.1µm, that are usually unnoticeable with traditional stains

Quantifiable Data

Provide fine measurements of disease progression and regression

3D Scanning

Realistic and 3D visualization of cellular and extracellular matrix architecture

Reproducible Staging

Eliminate inter- and intra-observer discrepancy

Multi-organ Applications

Able to extend to multiple connective tissues (e.g. liver, kidney, brain, lung, breast, colon, prostate, skin, heart, etc) and oncology studies