Research in Focus
A new study published in Nature Communications demonstrates how AI-powered digital pathology can provide a more detailed view of MASH progression and treatment response in preclinical studies. Researchers from Merck & Co., Inc. and MSD Singapore, with with hepatology expertise from VCU Stravitz-Sanyal Institute for Liver Disease and Metabolic Health, combined conventional histology with HistoIndex’s stain-free Second Harmonic Generation (SHG) imaging technology to examine the spatial relationships between steatosis, inflammation and fibrosis. The findings highlight how advanced tissue analysis with qFibrosis® can support the selection of fit-for-purpose disease models and enable more informed evaluation of therapeutic candidates in early-stage studies.
Read the full article here.
Events Highlights
A*STAR – Agency for Science, Technology and Research’s inaugural Portfolio Day
Our CEO Dr. Gideon Ho, PhD joined the fireside chat organised by A*STAR to share his insights from transforming deep-tech innovation into globally oriented business.
Team Highlights
This August our team retreat brought our HistoIndex colleagues together for action-packed team-building activities and shared experiences in Kuala Lumpur, Malaysia.
Recent publications
HistoIndex continues to advance liver disease research and contribute meaningful evidence to the growing body of scientific literature.
See the most recent publications below:
AI digital pathology as a key tool providing in-depth understanding of the progression and regression of MASH and fibrosis in male mouse models. Saigal, Ashmita, et al., Nature Communications 17.1 (2026): 6964. | Read article here
Steatosis in Cirrhosis: A Prognostic Marker for Liver‐Related Outcomes in Metabolic‐Dysfunction Associated Steatotic Liver Disease. Pei, Yiying, et al., Liver International 46.9 (2026): e70828. | Read article here
The Asian Pacific Association of the Study of the Liver expert survey on artificial intelligence-assisted reporting of liver histopathology in metabolic dysfunction associated fatty liver disease. Elangovan, H., et al., Hepatology International (2026): 1-11. | Read article here
Upcoming Conferences
Don’t miss out – catch us at our upcoming events and conferences:
AASLD The Liver Meeting 2026 | November 5-9, 2026 | Denver, Colorado
For questions or more information, please contact us at info@histoindex.com.
More exciting updates in our next edition – stay tuned!