News Room

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Boston-Piranha Tank International & Health-Tech Networking Event (1st Event)
7 high performing Life Science Companies from Singapore will compete for your feedback in a "Piranha Tank" format. This event is free, but registration is required. A chance to win an Apple Watch.VIEW MORE
New Jersey - Piranha Tank International & Health-Tech Networking Event (2nd Event)
7 high performing Life Science Companies from Singapore will compete for your feedback in a "Piranha Tank" format. This event is free, but registration is required. A chance to win an Apple Watch.VIEW MORE
Webinar : Fibro-C-Index
Fibro-C-Index: A Unique Quantitative Approach To Assess Liver Fibrosis Progression (stain-free!)VIEW MORE
Latest Paper of Histoindex's Genesis is published in the Scientific Reports
Published on 11th August 2015 - Title of Paper "Automated Biphasic Morphological Assessment of Hepatitis B-related Liver Fibrosis using Second Harmonic Generation Microscopy" VIEW MORE
Low cost and compact nonlinear (SHG/TPE) laser scanning endoscope for bio-medical application
This paper was published in Progress in Biomedical Optics and Imaging - Proceedings of SPIEVIEW MORE
Singapore Celebrates SG50!
Histoindex wishes Singapore a very Happy 50th Birthday!VIEW MORE
Another Webinar Discussions
Join us on this webinar where Dr. Gideon Ho and Dr. Mathieu Petitjean will briefly introduce the theory and the practical aspects of SHG, coupled with TPEF, for research application in pharmaceutical development. VIEW MORE
HistoIndex CEO, Dr. Gideon Ho Is Featured on Social Media
As part of the IE Singapore #SgGoesGlobal series, Dr. Gideon Ho, CEO of Histoindex Pte. Ltd., had the privilege to be invited to do an interview and a video to share on a success story to venture overseas as a Singapore SME, on Histoindex's technology and its Genesis200 Imaging system. This interview was aired on Channel News Asia on 1st July 2015.VIEW MORE
Come Join us on Webinar!
Both Dr. Gideon Ho (from Histoindex Pte. Ltd, Singapore) and Dr. Mathieu Petitjean (from PharmaNest, US), will host a webinar on "Collagen Characterization and Quantification with Non-linear Imaging System"..VIEW MORE
Digestive Diseases Week 2015 in USA
16th-19th May 2015 - Digestive Diseases Week 2015, Washington DC, USA.VIEW MORE
Chinese Medical Journal - Review Article
Published on 20th January 2015 - "Current Strategies for Quantitating Fibrosis in Liver Biopsy".VIEW MORE
Genesis Imaging Service - Inauguration Event
28th May 2015 - Histoindex's partner in the United States, PharmaNest, will celebrate its inauguration event with free discussion on the tissue samples' imaging results. VIEW MORE
Research Partnership between HistoIndex and the Institute of Molecular and Cell Biology (IMCB), A*STAR
1st May 2015 - HistoIndex and IMCB are embarking on a collaboration to refine image acquisition of stain-free tissue samples of various human diseases and animal disease models, and to conduct processing and analysis in 2D/3D of the stain-free images acquired from HistoIndex Genesis®200 multiphoton imaging system. VIEW MORE
HistoIndex is 5 years old today!
Histoindex Pte. Ltd. is celebrating its 5th year in the manufacturing and distribution of optical medical imaging technologies.VIEW MORE
We Are ISO 13485 Certified!
13th March 2015 - 12th March 2018 - HistoIndex's core product, Genesis, is certified with ISO 13485!VIEW MORE
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Wang Y, Huang W, Li R, Yun Z, Zhu Y, Yang J, Liu H, Liu Z, Feng Q, Hou J. "Systematic Quantitation of Histologic Patterns Shows Accuracy in Reflecting Cirrhotic Remodeling". J Gastroenterol Hepatol. 2017 Jan 9. doi: 10.1111/jgh.13722. [Epub ahead of print]
Wang Y, Vincent R, Yang J, Asgharpour A, Liang X, Idowu MO, Contos MJ, Daitya K, Siddiqui MS, Mirshahi F, Sanyal AJ, “Dual-photon microscopy-based quantitation of fibrosis-related parameters (q-FP) to model disease progression in steatohepatitis”. Hepatology. 2017 Jun;65(6):1891-1903. doi: 10.1002/hep.29090. Epub 2017 Apr 28.
Tong-Hong Wang, Tse-Ching Chen, Xiao Teng, Kung-Hao Liang & Chau-Ting Yeh, “Automated biphasic morphological assessment of hepatitis B-related liver fibrosis using second harmonic generation microscopy"  Scientific Reports, 5:12962; DOI: 10.1038/srep12962;
Liu, J., Lim, K. C., Li, H., Seck, H. L., Yu, X., Kok, S. W., et al. (2015), “Low cost and compact nonlinear (SGH/TPE) laser scanning endoscope for bio-medical application."  Progress in Biomedical Optics and Imaging - Proceedings of SPIE, 9304, 93041K-.
Manu Jain, MD; Brian D. Robinson, MD; Maria M. Shevchuk, MD; Amit Aggarwal, PhD; Bekheit Salamoon, MBBS; Justin M. Dubin, BS; Douglas S. Scherr, MD; Sushmita Mukherjee, PhD, Ms, “A Potential Intraoperative Tool for the Detection of Carcinoma In Situ in Human Bladder."  Arch Pathol Lab Med. 2015; 139:796-804;
David Sevrain, Matthieu Dubreuil, Grace Elizabeth Dolman, Abed Zaitoun, William Irving, Indra Neil Guha, Christophe Odin, and Yann Le Grand, “Evaluation of area-based collagen scoring by nonlinear microscopy in chronic hepatitis C-induced liver fibrosis 2015."  Biomed. Opt. Express, 1209-1218 (2015).
Jolanta Jedrzkiewicz, Mary P Bronner, Erinn Downs-Kelly, Jessica Kohan, Leslie Rowe, Dean Tai, Mohamed Salama.
“Digital Whole Slide Imaging and Two Photon Microscopy for Liver Fibrosis Scoring and Quantification."  Modern Pathol. 2015; 28(2):167A.
Rowe L, Etman A, Kohan J, Prchal J, Ho G, Liu DQ, Salama M.
“Stain-free detection of bone marrow fibrosis using two photon excitation and second harmonic generation microscopy."  Modern Pathol. 2015; 28(2):523A.
Sun W, Chang S, Tai DC, et al.
“Nonlinear optical microscopy: use of second harmonic generation and two-photon microscopy for automated quantitative liver fibrosis studies.” Journal of biomedical optics. 2008;13(6):064010.
Tai DC, Tan N, Xu S, et al.
“Fibro-C-Index:comprehensive, morphology-based quantification of liver fibrosis using second harmonic generation and two-photon microscopy.” Journal of biomedical optics. 2009; 14(4):044013.
Xu S, Wang Yi, Tai DC, et al.
“qFibrosis: A fully-quantitative innovative method incorporating histological features to facilitate accurate fibrosis scoring in animal model and chronic hepatitis B patients.” Journal of hepatology. 2014.
Strupler, M., Hernest, M., Fligny, C., Martin, J. L., Tharaux, P. L., and Schanne-Klein, M. C. (2008)
“Second harmonic microscopy to quantify renal interstitial fibrosis and arterial remodeling.” Journal of biomedical optics 13, 054041
Abraham T, Hirota JA, Wadsworth S, Knight DA.
“Minimally invasive multiphoton and harmonic generation imaging of extracellular matrix structures in lung airway and related diseases. Pulmonary pharmacology & therapeutics.” 2011;24(5):407-96.
Tilbury K, Lien CH, Chen SJ, Campagnola PJ.
“Differentiation of Col I and Col III isoforms in stromal models of ovarian cancer by analysis of second harmonic generation polarization and emission directionalit.” Biophysical journal. 2014;106(2):354-65.
Conklin MW, Eickhoff JC, Riching KM, et al.
“Aligned collagen is a prognostic signature for survival in human breast carcinoma.” The American journal of pathology. 2011;178(3):1221-32.

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